It really depends on what you plan to use the domain for but as a general answer .org is usually the best.
Google most certainly does pay more attention to sites with the keyword phrase in the domain itself. However... If you put a company/trademark...
I need a few articles on compounding pharmacies, if you can write in this niche let me know.
Don't waste money buying Google ads for a local niche. Taking over the first page first position spot is a frigging cake walk for a local niche...
If your site targets a high paying Adsense niche then stick with Adsense but if you are only getting crappy 3 cent clicks give Chitika a shot --...
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